Sister, Sister is an American television sitcom starring identical twins Tia and Tamera Mowry. It aired from 1994 to 1999. The premise of the show was that the girls (playing characters Tia Landry and Tamera Campbell) were separated and adopted at birth. One was adopted by a single mother while the other was adopted by a couple, although the mother died a short time later. The two accidentally found each other fourteen years later and reunited.

Created by Kim Bass, Gary Gilbert and Fred Shafferman, the series was produced by de Passe Entertainment and Paramount Network Television. The cast, along with Tia and Tamera Mowry, also featured Jackee Harry as Tia’s mother, Tim Reid as Tamera’s father, and Marques Houston as their annoying neighbor. RonReaco Lee and Deon Richmond joined the main cast in the fifth season.

Sister, Sister was picked up by ABC as a midseason replacement and debuted on April 1, 1994 as part of the network’s TGIF comedy lineup. The show later moved to a new timeslot for the 1994-95 season, but ABC announced that it was cancelling the program due to low ratings and its final episode aired April 28, 1995. The WB, which was still in its infancy in 1995, picked up Sister, Sister to replace the cancelled Muscle on its Wednesday night lineup of shows and the third season debuted on September 6, 1995. The program found its niche as part of The WB’s lineup and aired for four additional seasons on the network, with the final episode airing on May 23, 1999.

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